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CASE REPORT
Year : 2022  |  Volume : 9  |  Issue : 4  |  Page : 156-160

Lymphoepithelioma-like cholangiocarcinoma mimicking hepatocellular carcinoma imaging features in a young patient with Hepatitis B virus infection: A case report and literature review


1 Division of Gastroenterology and Hepatology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, Taiwan
2 Division of Gastroenterology and Hepatology, Department of Internal Medicine, MacKay Memorial Hospital; MacKay Junior College of Medicine, Nursing and Management, Taipei; MacKay Medical College, New Taipei, Taiwan
3 MacKay Junior College of Medicine, Nursing and Management; Department of Pathology, MacKay Memorial Hospital, Taipei, Taiwan
4 Division of Gastroenterology and Hepatology, Department of Internal Medicine, MacKay Memorial Hospital; MacKay Junior College of Medicine, Nursing and Management; MacKay Medical College, New Taipei; Institute of Traditional Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan

Correspondence Address:
Dr. Ching-Wei Chang
Division of Gastroenterology, Department of Internal Medicine, MacKay Memorial Hospital, No. 92, Sec. 2, Chung-Shan North Road, Taipei
Taiwan
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2311-3006.362639

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Lymphoepithelioma-like cholangiocarcinoma (LEL-CC) is a rare variant of intrahepatic cholangiocarcinoma. Only a few cases of LEL-CC have been reported, and the understanding of LEL-CC remains limited. Herein, we describe a case involving a 38-year-old Asian man with hepatitis B virus infection and LEL-CC. The patient's liver tumor was incidentally discovered during routine abdominal ultrasonography without obvious clinical signs or symptoms. Dynamic magnetic resonance imaging (MRI) revealed features of hepatocellular carcinoma and he underwent laparoscopic partial hepatectomy. Histologically, the liver tumor exhibited a lymphoepithelioma-like appearance and features of cholangiocarcinoma with Epstein–Barr virus infection.


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