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Year : 2021  |  Volume : 8  |  Issue : 4  |  Page : 148-151

Pleural effusion as the initial presentation of synchronous small lymphocytic lymphoma and non-small cell lung cancer

1 Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan
2 Department of Pathology, National Taiwan University Cancer Center, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan
3 Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan

Correspondence Address:
Dr. Chao- Hung Wei
Department of Oncology, National Taiwan University Hospital, No. 7, Zhongshan South Road., Zhongzheng., Taipei 100
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/JCRP.JCRP_20_21

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We report a case of a 64-year-old woman who presented with chronic cough for 2 months. A chest X-ray showed new-onset left pleural effusion, and chest computed tomography confirmed left pleural effusion in addition to small ground-glass nodules in both lungs. Analysis of the pleural effusion including culture and cytology did not show specific findings at a local hospital. Due to suspected lung cancer with malignant pleural effusion, thoracoscopic surgery was performed. Histopathological and immunohistochemical examinations revealed Stage I lung adenocarcinoma and concurrent primary pulmonary small lymphocytic lymphoma (SLL). This is a very rare case of primary pulmonary SLL and a concurrent lung adenocarcinoma.

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