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CASE REPORT
Year : 2021  |  Volume : 8  |  Issue : 3  |  Page : 117-122

Disseminated nocardiosis coinfection with extrapulmonary tuberculosis in a patient with metastatic thymoma: A case report and literature review


Division of Hematology and Oncology Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan

Correspondence Address:
Dr. Ren-Hua Ye
Division of Hematology and Oncology Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Chenggong Rd., Neihu Dist., Taipei
Taiwan
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JCRP.JCRP_10_21

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Patients with metastatic thymoma postintensive chemotherapy and radiotherapy are prone to opportunistic infectious diseases. Disseminated nocardiosis is a rare disease; however, its incidence has increased in recent years due to the growing population of immunocompromised hosts. We present the first report of Nocardia beijingensis infection with extrapulmonary tuberculosis coinfection causing muscular and brain abscesses in a patient with metastatic thymoma postintensive chemotherapy and radiotherapy. This case illustrates the possibility of coinfection with two pathogens and the difficulty in establishing a rapid diagnosis. Awareness of opportunistic infections and the early initiation of appropriate antibiotic therapy are important for the treatment of immunocompromised patients with infectious diseases.


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