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CASE REPORT
Year : 2021  |  Volume : 8  |  Issue : 1  |  Page : 26-28

An advanced-stage large-cell neuroendocrine lung carcinoma with intramedullary spinal metastases detected by positron emission tomography


1 Department of Hematology and Oncology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan
2 Department of Nuclear Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan; Department of Medical Imaging and Radiological Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan
3 Department of Hematology and Oncology, Chang Gung Memorial Hospital at Linkou; Department of Internal Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan

Correspondence Address:
Dr. Shao- Ming Yu
Department of Hematology and Oncology, Chang Gung Memorial Hospital at Linkou, No. 5 Fu-Hsing Street, Kwei-Shan Hsiang, Taoyuan 333
Taiwan
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JCRP.JCRP_28_20

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Large-cell neuroendocrine carcinoma (LCNEC) is a rare form of lung cancer with an aggressive behavior that frequently metastasizes to liver, brain, and bone. Intramedullary spinal cord metastasis (ISCM) is a rare clinical presentation of solid cancer and always indicates a dismal prognosis. This article presents a 72-year-old male patient diagnosed with an advanced-stage LCNEC who initially presented with ISCM that was diagnosed by positron emission tomography-computed tomography (PET-CT). This case demonstrates the diagnostic performance of PET-CT for ISCM. PET may be an alternative diagnostic modality for patients intolerant or unable to receive magnetic resonance imaging study to detect ISCM in those with LCNEC.


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